Emodin (AE), a hydroxyanthraquinone present in Aloe vera leaves, has a specific in vitro and in antineuroectodermal tumor
activity. The growth of human neuroectodermal tumors is inhibited in
mice with severe combined immunodeficiency without any appreciable toxic effects on the animal.Taking into account its unique
cytotoxicity profile and mode of action, AE might represent a
conceptually new lead antitumor drug.
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