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International Logistic Service 97% berberine hcl Barberry berberis vulgaris extract berberine hydrochloride powder
|
Product name
|
Berberine Hydrochloride/ (Berberine Sulfate) |
Appearance
|
Yellow needle-like crystals |
|
Botanical Source
|
Root |
Test Method
|
Titrimetric / HPLC
|
|
Specification
|
90%,97%, 98% |
Mesh
|
100% pass 80 mesh
|
|
Application
|
Health Care
|
Shelf Life
|
2 years
|
| Solubility: |
Soluble in water, insoluble in benzene, ether and chloroform
|
||
| Item |
Grade |
Resource |
Specification |
| Berberine HCL |
Human Grade(CP2005) |
Fibraurea recisa Pierre |
97% (Titrimetric) 91%-92%(HPLC) |
|
Human Grade(CP2015) |
Phellodendron |
98%(CP2015)(Titrimetric) 95%-97%(HPLC) |
|
|
Veterinary Grade |
Fibraurea recisa Pierre |
90%(Titrimetric) 30%(HPLC) |
|
| Berberine Sulfate | Pharmaceutical grade |
Phellodendron |
98%(Titrimetric) 95%(HPLC) |
| 1. Treatment of irritable bowel syndrome | It is found that berberine is a calcium channel antagonist with a certain effect, which inhibits the entry of Ca into cells, and has a decoupling effect on the excitatory contraction process of intestinal tissue. It is effective in treating diarrhea caused by irritable bowel syndrome. | |
| 2. Used for cardiovascular disease | ||
| 2.1 Anti-arrhythmia | Berberine hydrochloride has a good effect on ventricular and supraventricular tachyarrhythmias caused by various reasons. Its mechanism of action is related to reducing myocardial autonomy, prolonging the duration of action potential and effective refractory period, and eliminating the impulse of reentry. | |
| 2.2 Anti-heart failure | Berberine hydrochloride may extend the time course of the action potential of myocardial cells and promote the increase of calcium ion influx, resulting in increased myocardial contractility and decreased peripheral resistance, thereby achieving the purpose of treating heart failure. | |
| 2.3 Lower blood pressure | The mechanism of berberine lowering blood pressure is caused by the enhancement of acetylcholine effect and the expansion of blood vessels through anticholinesterase | |
| 2.4 Lowering blood lipids | The blood lipid-lowering effect of berberine hydrochloride is to lower blood lipids by acting on the 3UTR region to stabilize the low-density lipoprotein receptor Mrna (messenger ribonucleic acid) at the post-transcriptional level. | |
| 2.5 Lower blood sugar | Treating type 2 diabetes with berberine hydrochloride combined with metformin can significantly reduce the levels of diabetes inflammatory markers such as sCRP and TNFα, effectively improve insulin resistance and exert a good hypoglycemic effect. | |
| 3. Anti-tumor | Berberine hydrochloride may block the cell cycle, inhibit the activity of activator protein-1 (AP-1) and urokinase-type plasminogen activator (u-PA), and inhibit the activity of N-acetylase (NAT) , Inhibit the activity of cyclooxygenase-2 (COX-2), reduce the level of interleukin-6 (IL-6), and form a double-stranded structure with DNA to achieve anti-tumor effects | |
| 4. Application in living donor organ transplantation | In animal experiments, the combination of berberine and cyclosporine A has a synergistic effect on the prevention of acute rejection after heart transplantation in rats [20], significantly prolonging the survival time of experimental mouse skin grafts and enhancing cyclosporine A's anti-rejection effect | |
| Berberine- 1HNMR Berberine- 13CNMR |
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| Berberine Chloride IR1 & IR2 |
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| Our Certification of Analysis |
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Xi'an Ginhall Biotech Co., Ltd. is a national manufacturer of Cosmetics Raw Material and Plant Extract with well-equipped testing facilities and strong technical force. With a wide range, good quality, reasonable prices and stylish designs, our products are extensively used in Beauty Makeup industry and other industries. Our products are widely recognized and trusted by users and can meet continuously changing economic and social needs. We welcome new and old customers from all walks of life to contact us for future business relationships and mutual success. Xi’an Ginhall Biotech Co., Ltd. is committed to the development, production and sales of natural plant extracts, focusing on providing innovative products and innovative services to customers in the pharmaceutical, health food and cosmetics industries.
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