Great Cosmetics Raw Material magnolia officinalis bark extract Magnolol 98%

Magnolol and honokiol are the two main active ingredients of traditional Chinese medicine Magnolia, and have a wide range of pharmacological effects such as antibacterial, anti-inflammatory, anti-tumor muscle relaxation,cholesterol reduction and anti-aging. As early as 1930, Japan’s Sugiyra first isolated magnolol from the bark of Chinese magnolia, and proved that this ingredient is also contained in Japanese magnolia, but the amount is very low. In 1973, Fujita successively isolated magnolol and its isomers and magnolol from Japanese Magnolia and Magnolia.

Specification:

Pharmacology Of Magnolia Bark extract Powder

Effects on the digestive system

The extract of magnolia officinalis officinalis could inhibit the formation of salt-acid ulcer in mice. Honokiol, the active ingredient of Magnolol, can inhibit gastric acid secretion and resist ulcer. Magnolol can obviously fight diarrhea in sensene-leaved mice and promote bile flow in rats, indicating that Magnolol can promote digestive system as well as wenli medicine. Magnolia officinalis treating food, cold and damp dysentery, temperature in pain.

Analgesic and anti-inflammatory pharmacological effects

Magnolia officinalis is an aromatic and wet herb with analgesic and anti-inflammatory activities. Magnolia officinalis ethanol extract 5g/kg and 15g/kg have significant analgesic effects, significantly reduce the increase of capillary permeability in the abdominal cavity of mice caused by acetic acid, and significantly inhibit the ear swelling of mice caused by xylene and the paw swelling of mice caused by carrageenin. The experiment shows that magnolia officinalis has obvious anti-inflammatory and analgesic effects.

Central and peripheral muscle relaxation and antispasmodic effect

Magnolia officinalis is often used for extreme nervous, excited state and cause unknown vibration. Magnolol, the extract of magnolia officinalis, has the effect of blocking neuromuscular junction and can induce the central muscle relaxation similar to that of myophenol. And honokiol have sedative and anti-anxiety effects. At ultra-high doses, beta eucalyptus alcohol and diphenyl ethyl ureide sodium showed stronger effects in preventing electroconvulsive seizures. It is expected that beta eucalyptus alcohol can be used as a synergistic therapy in antiepileptic therapy or antiepileptic therapy with diphenyl ethyl ureide sodium.

Function Of Magnolia Bark extract Powder 

1.Powerful antioxidant in cardiovascular diseases;
2.Inhibit bacteria growth and viral infection;
3.Alleviate anxiety, improves sleep and relieves insomnia;
4.Anti-tumor and anti-cancer;
5.Anti-inflammatory and anti-canker;
6.Protect the brain from Alzheimer's disease;
7.Anti-dental caries and anti-periodontal disease;
8.Cure the habit of tobacco.

Application Of Magnolia Bark extract Powder

Pharmaceutical hygiene products & antimicrobial agents	Daily chemical wash & care application	Cosmetic applications
Magnolol Honokiol, the active component of magnolia officinalis extract, can be used as an antibacterial agent (gram-negative bacteria and acid-resistant bacteria) and can be used to prevent and treat acne.	Oral hygiene products to fight tooth decay, inhibit tooth decay. The inhibition of Magnolol Honokiol on NF-cB cells proved to improve the function of skin immune cells and had anti-inflammatory effect.	The inhibition of Magnolol Honokiol on NF-cB cells proved to improve the function of skin immune cells and had anti-inflammatory effect. Magnolol Honokiol can also be used as an antioxidant and skin whitening agent.

 

Pharmaceutical applications: gastrointestinal drugs, topical creams, lotions, etc., as Huoxiangzhengqi water.
Animal drugs and feed applications: gastrointestinal drugs, feed additives fatten.
Daily necessities applications: toothpaste, chewing gum, mouthwash, shampoo, shower gel.
Application of health care products: gastrointestinal health, help sleep, lose weight.

ITEM	SPECIFICATION	TEST METHOD
Active Ingredeints
Assay(Magnolol)	>98%	HPLC
Physical Control
Identification	Positive	TLC
Appearance	Off-White powder	Visual
Odor	Characteristic	Organoleptic
Taste	Characteristic	Organoleptic
Sieve Analysis	100% pass 80 mesh	80 Mesh Screen
Moisture Content	NMT 1.0%	Mettler toledo hb43-s
Chemical Control
Arsenic (As)	NMT 2ppm	Atomic Absorption
Cadmium(Cd)	NMT 1ppm	Atomic Absorption
Lead (Pb)	NMT 3ppm	Atomic Absorption
Mercury(Hg)	NMT 0.1ppm	Atomic Absorption
Heavy Metals	10ppm Max	Atomic Absorption
Microbiological Control
Total Plate Count	10000cfu/ml Max	AOAC/Petrifilm
Salmonella	Negative in 10 g	AOAC/Neogen Elisa
Yeast & Mold	1000cfu/g Max	AOAC/Petrifilm
E.Coli	Negative in 1g	AOAC/Petrifilm

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